Cloning the Flagellin Genes of Campylobacter Upsaliensis
Campylobacter upsaliensis is fast becoming recognised as a significant human pathogen, causing, amongst other symptoms, diarrhoea, bacteraemia and respiratory problems. The organism was first described by Sandstedt et al. 8 from dogs with or without diarrhoea and later from asymptomatic cats by Fox et al. 1. In subsequent studies, C. upsaliensis was isolated from human faecal samples3,6,9,11,12, human blood5,7,11, a breast abscess2 and foetoplacental tissues4. However, relatively little is known about the virulence determinants of C. upsaliensis, and the mechanisms by which it causes disease remain unclear.
KeywordsPstI Site Flagellin Gene Human Faecal Samples3 Flagellin Protein Flagellin Subunit
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- 3.Goossens, H., Pot, B., Vlaes, L., Van Den Borre, C., Van Den Abbelle, R., Van Naelten, C., Levy, J., Cog-niau, H., Marbehant, P., Verhoef, J., Kersters, K., Butzler, J., & Vandamme, P. (1990). J. Clin. Microbiol, 1039-1046.Google Scholar