Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular pp 97-105 | Cite as
Analytical Approaches Adopted during the Development of Flurbiprofen
Chapter
Abstract
Brief mention is made of the assay and stereoselective metabolism of ibuprofen. The NSAID⌽ given attention in this article is flurbiprofen, the development of which entailed successive assay methods. That outlined below was used when the number of samples to be assayed was escalating.
Keywords
Propanoic Acid Maximum Daily Dose Drug Development Programme Stereoselective Metabolism Typical HPLC Chromatogram
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Abbreviation
- NSAID
non-steroidal anti-inflammatory drug
- PFB
pentafluorobenzyl
- RP
reversed phase
- i.s.
internal standard
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© Springer Science+Business Media New York 1988