The Regulatory Role of Dopaminergic Pathways in the Mammalian Outer Retina
This chapter examines the role of dopaminergic pathways in the physiology of the mammalian retina and reviews the current literature regarding this important regulatory retinal pathway. It was my (M.W.H.) good fortune to join Professor Ikeda’s group in 1988, where I began to develop in vitro preparations of the mammalian retina for intracellular recording. This chapter is illustrated by data from neuropharmacological experiments performed in the Vision Research Unit during the period of 1988–1993.
KeywordsReceptive Field Horizontal Cell Dopaminergic Pathway Mammalian Retina Control Retina
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- Bok, D. and Hall, M.O. (1971) The role of pigment epithelium in the etiology of inherited retinal dystrophy in the rat, J. Cell Biol. 14:73–109.Google Scholar
- Domenichi, L., Trimarchi, C., Piccolino, M., Fiorentini, A. and Maffei, L. (1985) Dopaminergic drugs improve human visual contrast sensitivity, Human Neurobiol. 4:195–197.Google Scholar
- Hankins, M.W. and Ikeda, H. (1991b) The role of dopaminergic pathways at the outerplexiform layer of the mammalian retina, Clin. Vision Sci. 6:87–93.Google Scholar
- Hankins, M.W., Rowe, J.S. and Ruddock, K.H. (1985) Properties of amino acid binding sites on horizontal cells determined by electrophysiological studies on the isolated roach retina. In: Neurocircuitry of the Retina A Cajal Memorial (Ed. A. Gallego and P. Gouras), Elsevier-N.Y, pp 99-108.Google Scholar
- Hankins, M.W., Jones, R.J.M. and Ruddock, K.H. (1995) Diurnal variation in the b-wave component of the human electroretinogram (ERG), J. Physiol. 483:42PGoogle Scholar
- Hamois, C. and DiPaolo, T. (1990) Decreased dopamine in the retinas of patients with Parkinson’s disease, Invest. Ophthalmol. Vis. Sci. 31:2473–2475.Google Scholar
- Ikeda, H., Priest, T.D., Robbins, J. and Wakakuwa, K. (1986) Silent dopaminergic synapse at feline retinal ganglion cells, Clin. Vis. Sci., 1:25–38.Google Scholar