Histoplasmosis is worldwide in distribution but is more prevalent in certain parts of North and Latin America. Histoplasma capsulatum var. capsulatum grows best in soil contaminated with bat or bird droppings. Patients often report exposure to microfoci-contaminated materials. Spores or mycelial fragments are inhaled and cause localized or patchy pneumonitis. Hematogenous dissemination to other tissues commonly follows during the first 2 weeks of infection before specific immunity has developed.
KeywordsChronic Obstructive Pulmonary Disease Chest Radiograph Histoplasma Capsulatum Bird Dropping Pulmonary Histoplasmosis
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