More Information from Your Circular Dichroism
The purpose of this meeting is to discuss how circularly polarized synchrotron radiation could be used to learn more about molecules. Synchrotron radiation opens the possibility for high fluxes of circularly polarized light at very high energy. Thus the exciting new techniques such as circular intensity differential scattering, and circular differential microscopy would benefit greatly from a synchrotron ring generating circular polarized light. I believe such radiation will prove equally useful for that standard technique, circular dichroism of electronic absorption bands. Time constants of 10 to 60 seconds are the norm on conventional instrumentation so that it may take a number of hours to scan a CD spectrum. The large increase in light intensity from a synchrotron source allows shorter time constants and more rapid scanning, and smaller spectral slit widths for increased resolution. More rapid scanning offers the potential of doing kinetic studies on changes in secondary structure for biopolymers.
KeywordsSecondary Structure Hyaluronic Acid Circular Dichroism Singular Value Decomposition Synchrotron Source
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