Antimicrobial Susceptibility Tests: Testing Methods and Interpretive Problems

  • Patrick R. Murray
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 349)

Abstract

Infectious diseases are a leading cause of morbidity and mortality in hospitalized patients. This fact places a tremendous burden on the clinical microbiology laboratory to diagnose rapidly the etiologic agent(s) responsible for a patient’s infection and provide therapeutic guidance for eradication of the organism(s). Laboratories are asked not only to perform these tasks with precision and rapidity, but also in a cost-effective manner in an era of increasing emphasis on reduction of laboratory expenses. Physicians will pose the question — How accurately can antimicrobial susceptibility tests predict clinical outcome? At the same time, the microbiologists ask — What method should we use for performing susceptibility tests? What is the most accurate method? What is the most cost — effective method? What are the limitations of the in vitro tests? I will try to address these questions in the following discussion.

Keywords

Susceptibility Test Disk Diffusion Antimicrobial Susceptibility Test Disk Diffusion Test Diagn Microbiol Infect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Patrick R. Murray
    • 1
  1. 1.Washington University School of MedicineSaint LouisUSA

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