Inhibition of Proteinase 3 Activity by Peptides Derived from Human Epidermis

  • Oliver Wiedow
  • Jens Lüdemann
  • Bert Utecht
  • Enno Christophers
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

Elafin and antileukoprotease are potent peptide-like inhibitors of human leukocyte elastase and have been isolated from human skin and bronchial mucus. Elafin proved to be a potent inhibitor of proteinase 3, whereas other inhibitors of human leukocyte elastase such as antileukoprotease and eglin C proved to be much less effective.

Keywords

Complete Amino Acid Sequence Human Mucous Secretion Human Leukocyte Elastase Bronchial Mucus Medical Leech 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Oliver Wiedow
    • 1
  • Jens Lüdemann
    • 2
  • Bert Utecht
    • 2
  • Enno Christophers
    • 1
  1. 1.Department of DermatologyUniversity of KielKielGermany
  2. 2.Gesellschaft für angewandte BiotechnologieRaisdorfGermany

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