Little Evidence for Anti-Endothelial-Cell Antibodies in Microscopic Polyarteritis and Wegener’s Granulomatosis

  • M. Varagunam
  • A. C. Nwosu
  • D. Adu
  • C. Garner
  • C. M. Taylor
  • J. Michael
  • R. A. Thompson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

Sera from patients with a vasculitis and controls were investigated for the presence of anti-endothelial cell antibodies(AECA), anti- neutrophil cytoplasmic antibodies(ANCA) and anti-myeloperoxidase (MPO) antibodies. Only 19% of patients with Wegener’s granulomatosis and 2% of patients with microscopic polyarteritis had AECA. Our data suggests that AECA are a minor antibody system in vasculitis.

Keywords

Rheumatoid Vasculitis Microscopic Polyarteritis Minor Antibody Endothelial Cell Antibody Immunoflourescent Staining 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • M. Varagunam
    • 1
  • A. C. Nwosu
    • 2
  • D. Adu
    • 1
  • C. Garner
    • 1
  • C. M. Taylor
    • 1
  • J. Michael
    • 1
  • R. A. Thompson
    • 2
  1. 1.Renal Research LaboratoryQueen Elizabeth Hospital.EdgbastonBirminghamEngland
  2. 2.Regional Immunology LaboratoryEast Birmingham HospitalBirminghamEngland

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