Little Evidence for Anti-Endothelial-Cell Antibodies in Microscopic Polyarteritis and Wegener’s Granulomatosis
Sera from patients with a vasculitis and controls were investigated for the presence of anti-endothelial cell antibodies(AECA), anti- neutrophil cytoplasmic antibodies(ANCA) and anti-myeloperoxidase (MPO) antibodies. Only 19% of patients with Wegener’s granulomatosis and 2% of patients with microscopic polyarteritis had AECA. Our data suggests that AECA are a minor antibody system in vasculitis.
KeywordsRheumatoid Vasculitis Microscopic Polyarteritis Minor Antibody Endothelial Cell Antibody Immunoflourescent Staining
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