ANCA with Specificity for Lactoferrin in Systemic Lupus Erythematosus (SLE)

  • Renato A. Sinico
  • Cristiana Pozzi
  • Antonella Radice
  • Angela Tincani
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

Antibodies to lactoferrin were detected in about 20% of patients with SLE, irrespective of the presence of renal involvement and in 10% of patients with rheumatoid arthritis and in 19% of patients with scleroderma. We conclude that antilactoferrin antibodies may be found in different types of connective tissue disease. Their clinical significance in these diseases however remains to be elucidated.

Keywords

Systemic Lupus ERYTHEMATOSUS Systemic Lupus ERYTHEMATOSUS Patient Lupus Nephritis Connective Tissue Disease Renal Involvement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Jennette J.C. and Falk R.J., 1990, Antineutrophil cytoplasmic autoantibodies and associated diseases: a review. Am. J. Kidney Dis. 15: 517 - 529.PubMedGoogle Scholar
  2. Lesavre P., 1991, Antineutrophil cytoplasmic autoantibodies antigen specificity. Am. J. Kidney Dis. 18: 159 - 163.PubMedGoogle Scholar
  3. Pozzi C., Radice A., Rota S., Li Vecchi M. and Sinico R.A., 1991, Clinical significance of anti-lactoferrin antibodies in renal disease. Am. J. Kidney Dis. 202.Google Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Renato A. Sinico
    • 1
  • Cristiana Pozzi
    • 1
  • Antonella Radice
    • 1
  • Angela Tincani
    • 2
  1. 1.Divisione di NefrologiaOspedale S. CarloMilanoItaly
  2. 2.Servizio di Immunologia ClinicaSpedali CiviliBresciaItaly

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