Anti-Neutrophil Cytoplasmic Antibodies in Patients with Systemic Lupus Erythematosus

  • Monika Waldendorf
  • Mathias Schneider
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

Autoantibodies against neutrophil cytoplasmic antigens (ANCA) are found in patients with different kinds of systemic vasculitis and glomerulonephritis, both characteristic manifestations of systemic lupus erythematosus (SLE). The present study was designed to clarify the nature of ANCA seen in SLE patients and their correlation with the clinical findings.

Keywords

Systemic Lupus Erythematosus Systemic Lupus Erythematosus Patient Systemic Vasculitis Characteristic Manifestation Strong Nuclear Staining 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Byrgren, P., Rasmussen, N. and Wieslander, J. 1989, ANCA in glomerulonephritis, APMIS Supplement No. 6, Vol. 97: 43.Google Scholar
  2. Falk, R.J. and Jennet, J.C., 1988, Anti-neutrophil cytoplasmic autoantibodies with specifity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotising and crecentic glomerulonephritis, N Engi J Med 318, 1651.CrossRefGoogle Scholar
  3. Jennette, J.C., Wilkman, A.S. and Falk, R.J. 1989, Anti-Neutrophil Cytoplasmic AutoantibodyAssociated Glomerulonephritis and Vasculitis, Am J Pathol 135: 921–930.PubMedGoogle Scholar
  4. Lee, S.S., Adu, D. and Thomson, R.A. 1990, Anti-myeloperoxidase antibodies in systemic vasculitis, Clin exp Immunol 79: 41–46.PubMedCrossRefGoogle Scholar
  5. Naessberger, L., Sjoeholm, A.G., Jonsson, H., Sturfelt, G. and Akesson 1990, Autoantibodies against neutrophil cytoplasm components in systemic lupus erythematosus and in hydralazin induced lupus, Clin exp Immunol 81: 380–383.CrossRefGoogle Scholar
  6. Noelle, B., Specks, U., Luedemann, J., Rohrbach, M.S., DeRemmee, R.A. and Gross, W.L. 1989 ANn Int Med 111: 28–40.CrossRefGoogle Scholar
  7. Venning, M.C., Quinn, A., Broomhead, V. and Bird, A.G. 1990, Antibodies against neutrophils (c-ANCA and p-ANCA) are of distinct diagnostic diagnostic value in systemic vasculitis, Quart J Med 284: 1287–1296.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Monika Waldendorf
    • 1
  • Mathias Schneider
    • 2
  1. 1.Nephrologische Abteilung Medizinische Klinik IKlinikum Großhadern der Universität MünchenGermany
  2. 2.Innere Medizin Abteilung BUniversität MünsterGermany

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