Low Predictive Value of C-ANCA and Anti-α -Granule Antibody for Vasculitis in Hong Kong

  • John W. M. Lawton
  • S. S. Lee
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

One thousand sera, not previously tested for ANCA, were assayed for C-ANCA and anti-a-granule antibody. There was low concordance (23%) between the two assays in terms of positivity. Each assay gave a positive predictive value for systemic vasculitis (excluding SLE and other connective-tissue diseases) of not more than 20%.

Keywords

Kawasaki Disease Systemic Vasculitis Antineutrophil Cytoplasmic Antibody Normal Seron Positive ANCA 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • John W. M. Lawton
    • 1
  • S. S. Lee
    • 2
  1. 1.Department of PathologyUniversity of Hong KongHong Kong
  2. 2.Department of HealthHong Kong

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