Low Predictive Value of C-ANCA and Anti-α -Granule Antibody for Vasculitis in Hong Kong
One thousand sera, not previously tested for ANCA, were assayed for C-ANCA and anti-a-granule antibody. There was low concordance (23%) between the two assays in terms of positivity. Each assay gave a positive predictive value for systemic vasculitis (excluding SLE and other connective-tissue diseases) of not more than 20%.
KeywordsKawasaki Disease Systemic Vasculitis Antineutrophil Cytoplasmic Antibody Normal Seron Positive ANCA
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