Stable Liposomes Formed from Archaeal Ether Lipids
Liposomes have application in serving as a support, or matrix, to form two dimensional crystals from those proteins which normally interact with the cytoplasmic membrane (Wingfield et al., 1979). This interaction includes membrane proteins that are largely embedded within the lipid bilayer, others with relatively more surface area exposed, and surface proteins which interact either via a single transmembrane strand or via a covalently linked lipid (Andreas et al., 1992). Recently, Andreas et al. demonstrated the two-dimensional crystallization of a solubilized surface protein from Comamonas acidovorans on lipid vesicles.
KeywordsPressure Extrusion Pore Filter Extreme Halophile Multilamellar Structure Polar Ether
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- Baumeister, W., Wildhaber, I., and Phipps, B.M., 1989, Principles of organization in eubacterial and archaebacterial surface proteins, Can. J. Microbiol. 35: 215.Google Scholar
- Beveridge, T.J., Choquet, C.G., Patel, G.B., and Sprott, G.D., 1993, Freeze-fracture planes of methanogen membranes correlate with the content of tetraether lipids, J. Bacterial. 175: in press.Google Scholar
- Kates, M., 1990, Glyco-, phosphoglyco-and sulfoglycoglycerolipids of bacteria, in: “Glycolipids, Phosphoglycolipids, and Sulfoglycolipids”, M. Kates, ed., Plenum Press, New York.Google Scholar
- Lelkes, P.I., Goldenberg, D., Gliozzi, A., De Rosa, M., Gambacorta, A., and Miller, I.R., 1983, Vesicles from mixtures of bipolar archaebacterial lipids with egg phosphatidylcholine, Biochim. Biophy. Acta 33: 337.Google Scholar
- Morth, S., and Tindall, B.J., 1985, Variation of polar lipid composition within haloalkaliphilic archaebacteria, System. Appl. Microbio1.6:247.Google Scholar
- Ring, K., Henkel, B., Valenteijn, A., and Gutermann, R., 1986, Studies on the permeability and stability of liposomes derived from a membrane spanning bipolar archaebacterial tetraether lipid, in: “Liposomes as Drug Carriers”, K.H. Schmidt, ed., Georg Thieme Verlag, Stuttgart.Google Scholar
- Sprott, G.D., Meloche, M., and Richards, J.C., 1991, Proportions of diether, macrocyclic diether, and tetraether lipids in Methanococcus jannaschü grown at different temperatures, J. Bacterial. 173: 3907.Google Scholar