Renal Transplantation for Diabetic Nephropathy
Diabetes mellitus, in 1994, is the leading cause of end-stage renal disease (ESRD) in the United States (US), Japan, and most nations in industrialized Europe. All registries in Europe, Asia, and North America show that glomerulonephritis and hypertensive renal disease rank well below diabetes in frequency of diagnosis among new ESRD patients, substantiating Mauer and Chavers contention that »Diabetes is the most important cause of ESRD in the Western world «. The growth of both the total and diabetic population of ESRD patients in the US is depicted in figure 47–1. Data from 1990, the most recent calendar year report of the United States Renal Data System (USRDS), underscore this point. Of 165,363 patients — including 40,174 with diabetes (24.3%) — receiving either dialytic therapy or a kidney transplant in the US in 1990 – 45,153 developed ESRD during 1990 . There were 15,383 (34.0%) diabetics whose renal failure was attributed to diabetes in the new incidence group. Therefore, while the incidence of ESRD caused by diabetes is 62 per million out of a total for all diseases of 169 per million, the prevalence of diabetics among those undergoing ESRD treatment decreased to a smaller segment of the whole (152 per million out of a total of 618 per million).
KeywordsDiabetes Type Diabetic Nephropathy Renal Transplantation Kidney Transplant ESRD Patient
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