1,3-Difurfurylurea

  • A. L. Mndzhoian

Abstract

A mixture of 19.4 g (0.2 mole) of furfurylamine (see p. 60), b.p. 83°/85 mm, and 50 ml of 20% aqueous sodium hydroxide solution was prepared in a 250-ml four-necked round-bottomed flask fitted with mercury-sealed stirrer, reflux condenser, dropping funnel, and thermometer (see Notes). The mixture was kept at 0° and stirred continuously while a solution of 11–12 g (0.11–0.12 mole) of phosgene in 100 ml of dry benzene was added from the dropping funnel over a period of 60–90 minutes. When the addition was complete, the cooling bath was removed and the mixture was stirred at room temperature for 2.5–3 hours. The precipitated crystals of 1,3-difurfurylurea were filtered off, washed on the filter with 20 ml of water, and dried in the air. Recrystallization from 200 ml of boiling benzene gave 20.5–21.0 g (93.2–95.4%) of pure substance, m.p. 126–128°.

Keywords

Heterocyclic Compound Sodium Hydroxide Solution Pure Product Nickel Catalyst Reflux Condenser 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Literature Cited

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    W. Marckwald, Ber. 23, 3207 (1890).Google Scholar
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    U. S. Pat. 2,595,492 (1952) [C.A. 46, 7820a (1952)];Google Scholar
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    U. S. Pat. 2,673,859 (1954) [C.A. 49, 4015g (1955)].Google Scholar

Copyright information

© Springer Science+Business Media New York 1959

Authors and Affiliations

  • A. L. Mndzhoian

There are no affiliations available

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