Metabolic Changes Following Splenic Transplantation in a Case of Gaucher’s Disease
The fact that the highest activity of glucocerebrosidase is normally found in the spleen (2) has suggested the possibility of splenic transplantation as a means of enzyme replacement in Gaucher’s disease (1). Technically successful splenic homotransplantations have been reported by Starzl and co-workers in six patients with diseases other than lipidosis (3, 9).
KeywordsCeramide Level Phenyl Phosphate Skeletal Pain Royal Veterinary College Produce Cell Death
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