Application of Magnetic Particles in Immunoassays

  • Mary Meza
Chapter

Abstract

For many years, the immunological antibody-antigen interaction has been used to determine concentrations of analytes useful in medical diagnostics. Antibody or antigen is typically immobilized onto a solid phase, which traditionally has included filters, tubes, wells or plastic beads. The use of small magnetic particles as the solid phase has revolutionized the field of clinical chemistry by facilitating the development of more sensitive higher-throughput automated immunoassays. Many of today’s automated immunoassay systems rely on magnetic separation.

Keywords

Magnetic Particle Label Antibody Coated Particle Competitive Binding Assay Antigen Recognition Site 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Chan DW (1996). Immunoassay Automation: an updated guide to systems. San Diego, Academic Press.Google Scholar
  2. 2.
    Wild D (Ed) (1994). The Immunoassay Handbook. New York, Stockton Press.Google Scholar

Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Mary Meza
    • 1
  1. 1.Bangs Laboratories, Inc.FishersUSA

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