Variability of PCO2 Breath-by-Breath in Normal Man

  • Christopher B. Wolff
  • Durumee Hong
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 540)

Abstract

Ventilation is finely adjusted in relation to the metabolic needs of the body, with alveolar (and arterial) gas pressures maintained steady at rest and in submaximal exercise. Constancy of the mean alveolar PCO2 has been known for at least 80 years.1

Keywords

Carotid Body Submaximal Exercise Near Detector Coupler Unit Royal London Hospital 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    M. P. Fitzgerald and J. S. Haldane, The normal alveolar carbonic acid pressure in man. J. Physiol., 32, 486494 (1905).Google Scholar
  2. 2.
    C.B Wolff, T.J. Peters, J. Keating and W.N. Gardner, Effects of alcohol on respiratory variables in normal humans. Addiction Biology, 4, 223–228 (1999).PubMedCrossRefGoogle Scholar
  3. 3.
    G.F. Rafferty, J. Evans and W.N. Gardner, Control of expiratory time in conscious humans. J. Applied Physiology, 78, 1910–1920 (1994).Google Scholar
  4. 4.
    D Hong, Ventilation, VCO2 and PCO2 at rest and in submaximal exercise - values and breath-by-breath variability. MSc. Thesis, University of London, (2001).Google Scholar
  5. 5.
    A. M. S. Black, D. I. McCloskey and R. W. Torrance The responses of carotid bsody chemoreceptors in the cat to sudden changes of hypercapnic and hypoxic stimuli. Resp. Physiol., 13, 36–49 (1971).CrossRefGoogle Scholar
  6. 6.
    G. C.Coulter, M. D. Fischer, P. A. Robbins and D. C. Weir, The relation between the duration of respiratory cycles and the lung-to-carotid circulation time in exercise. J. Physiol.,307, 44P–45P (1980).abstractGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Christopher B. Wolff
    • 1
  • Durumee Hong
    • 2
  1. 1.Applied PhysiologySherrington SchoolLondonUK
  2. 2.The Academic Department of Sports MedicineThe Royal London HospitalLondonUK

Personalised recommendations