Clinical Use of Artificial Oxygen Carriers
Artificial oxygen carriers aim at improving oxygen delivery (DO2). Artificial oxygen carriers, therefore, may be used as an alternative to allogeneic blood transfusions or to improve tissue oxygenation and function of organs with marginal oxygen supply [1, 2]. Modified hemoglobin solutions and perfluorocarbon (PFC) emulsions are currently undergoing clinical testing. This chapter is based on a recent review article  where more detailed references may be found. Current knowledge of artifical oxygen carriers is based on published data from approximately 500–1000 patients treated with these compounds and a similar number of control patients. Unfortunately, there is still a significant amount of non-published data that renders the overall assessment of these solutions difficult.
KeywordsAutologous Blood Oxygen Carrier Allogeneic Blood Transfusion Blood Substitute Hemoglobin Solution
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