It is always a pleasure to present the keynote address because one has considerable latitude as to topic and content. This latitude is particularly appropriate for a discussion of enzyme engineering, because the initial interest in this field seems to have matured considerably over the past few years. Most of the simpler studies have been done and the obvious applications tested, yet much of the earlier promise of enzyme engineering still remains as undemonstrated potential. Although a review of some of the developments that have occurred since the 1973 conference appears appropriate, a strong argument for more innovative approaches to research and development in enzyme engineering seems of greater value for stimulating the proper evaluation and hopeful achievement of more of these potentials.
KeywordsApply Biochemistry Immobilize Enzyme Innovative Approach Diffusional Resistance Keynote Address
Unable to display preview. Download preview PDF.
- 1.WINGARD, L.B. Jr. “Enzyme Engineering”, Wiley-Interscience, New York, 1972.Google Scholar
- 2.PYE, E.K. and WINGARD, L.B. Jr. (eds) “Enzyme Engineering”, Vol 2, Plenum Press, New York, 1974.Google Scholar
- 3.CHIBATA, I. and TOSA, T. In “Immobilized Enzyme Principles” (Ed. Wingard, L.B. Jr., Katzir-Katchalski, E. and Goldstein, L.) Academic Press, New York, 1976. p. 329Google Scholar
- 5.BRUNNER, G., personal communication, 1973.Google Scholar
- 6.DIOGUARDI, N., de FRANCHIS, R., MARI, D., MORISI, F. and MARCONI, W. Digestion 10: 344, 1974.Google Scholar
- 10.VOLLER, A., personal communication, 1974.Google Scholar
- 11.HEDEN, C.-G., “Socio-Economic and Ethical Implications of Enzyme Engineering”, International Federation of Institutes for Advanced Study, Stockholm, Sweden, 1974.Google Scholar
- 12.SALMONA, M., SARONIO, C. and GARATTINI, S. (eds) “Insolubilized Enzymes”, Raven Press, New York, 1974.Google Scholar
- 11.MESSING, R.A. (ed) “Immobilized Enzymes for Industrial Reactors”, Academic Press, New York, 1975.Google Scholar
- 14.WINGARD, L.B. Jr., KATZIR-KATCHALSKI, E. and GOLDSTEIN, L. (eds) “Immobilized Enzyme Principles” (Applied Biochemistry and Bioengineering Vol. 1.) Academic Press, New York, 1976.Google Scholar
- 15.KAO-HSIANG, L., SHAO-KAI, C., WAN-RHU, S., SHU-FEN, K., LIEN-WAN, Y., SHU-FANG, L. and KAI-YU, Y. Acta Microbiologica Sinica 13: 31, 1973.Google Scholar
- 22.DAY, R.J., KINSEY, S.J., SEO, E.T., WELIKY, N. and SILVERMAN, H.P. Trans. N.Y. Acad. Sci. 34: 588, 1972.Google Scholar
- 24.ENGASSER, J.M. and HORVATH, C. In “Immobilized Enzyme Principles” (Eds. Wingard, L.B. Jr., Katzir-Katchalski, E. and Goldstein, L.) Academic Press, New York, 1976. p. 127Google Scholar