Breastfeeding, Body Mass Index, and Asthma and Atopy in Children

  • W. H. Oddy
  • J. L. Sherriff
  • N. H. de Klerk
  • G. E. Kendall
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 554)

Abstract

Asthma is the leading cause of hospitalization in Australian children and its prevalence is increasing worldwide (Peat & Li 1999). In developed nations the increase in prevalence of childhood asthma has been paralleled by an increase in childhood obesity (WHO 1998). There has been considerable debate as to whether formula-feeding is a risk factor for childhood obesity (von Kries et al. 2001). Furthermore, investigators have speculated that obesity may be a causal factor in the inception of childhood asthma and a number of studies have shown positive associations between body mass index (BMI=weight/(kg)/(m)2) or obesity with asthma (von Mutius et al. 2001). Breastfeeding has been shown to protect against overweight and obesity (von Kries et al. 1999; Hediger et al. 2001) as well as asthma in childhood (Oddy et al. 1999), although the relationship between breastfeeding and childhood asthma remains speculative (Wright et al. 2001).

Keywords

Propensity Score Childhood Obesity Childhood Asthma Exclusive Breastfeed Current Asthma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Drake C, Fisher L. Prognostic models and the propensity score. Int J Epidemiol 1995;24:183–187.PubMedCrossRefGoogle Scholar
  2. Hediger ML, Overpeck MD, Kuczmarski RJ, Ruan WJ. Association between infant breastfeeding and overweight in young children. JAMA 2001;285:2453–2460.PubMedCrossRefGoogle Scholar
  3. Newnham JP, Evans SF, Michael CA, Stanley FJ, Landau LI. Effects of frequent ultrasound during pregnancy: a randomised controlled trial. Lancet 1993;342:887–891.PubMedCrossRefGoogle Scholar
  4. Oddy WH, Holt PG, Sly PD, Read AW, Landau LI, Stanley FJ, Kendall GE, Burton PR. Association between breastfeeding and asthma in 6 year old children: findings of a prospective birth cohort study. BMJ 1999;319:815–819.PubMedCrossRefGoogle Scholar
  5. Peat JK, Li J. Reversing the trend: reducing the prevalence of asthma. J Allergy Clin Immun 1999;103:1–10.PubMedCrossRefGoogle Scholar
  6. Rosenbaum PR, Rubin DB. The central role of the propensity score in observational studies for causal effects. Biometrika 1983;70:41–55.CrossRefGoogle Scholar
  7. von Kries R, Koletzko B, Sauerwald T, von Mutius E, Barnert D, Grunert V, von Vos H. Breastfeeding and obesity: cross sectional study. BMJ 1999;319:147–150.CrossRefGoogle Scholar
  8. von Kries R, Hermann M, Grunert VP, von Mutius E. Is obesity a risk factor for childhood asthma? Allergy 2001;56:318–322.CrossRefGoogle Scholar
  9. von Mutius E, Schwartz J, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III. Thorax 2001 ;56:835–838.CrossRefGoogle Scholar
  10. [WHO] World Health Organization. Obesity: preventing and managing the global epidemic. Geneva: World Health Organization; 1998.Google Scholar
  11. Wright AL, Holberg CJ, Taussig LM, Martinez FD. Factors influencing the relation of infant feeding to asthma and recurrent wheeze in childhood. Thorax 2001;56:192–197.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • W. H. Oddy
    • 1
    • 2
  • J. L. Sherriff
    • 1
  • N. H. de Klerk
    • 2
  • G. E. Kendall
    • 2
  1. 1.Department of Nutrition, Dietetics and Food ScienceCurtin University of TechnologyAustralia
  2. 2.Centre for Child Health Research, TVW Telethon Institute for Child Health ResearchUniversity of Western AustraliaWest PerthAustralia

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