Tumors

  • Hervé Deramond
  • Claude Depriester
  • Jacques Chiras
  • Anne Cotten
  • Nathalie Boutry
  • Bernard Cortet

Abstract

Osteolytic metastases and myeloma are the most frequent malignant destructive lesions involving the spine. Affected patients often experience severe back pain and disability related to the vertebral fractures induced by these destructive lesions. The aim of percutaneous vertebroplasty (PV) in these disease processes is to produce pain relief and reinforcement by the injection of acrylic cement. This treatment may be used adjunctively with radiation therapy and chemotherapy.

Keywords

Multiple Myeloma Vertebral Body Spinal Cord Compression Percutaneous Vertebroplasty Axial Compute Tomography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Parlier-Cuau C, Champsaur P, Nizard R, et al. Percutaneous removal of osteoid osteoma. Radiol Clin North Am 1998; 36(3):559–566.PubMedCrossRefGoogle Scholar
  2. 2.
    Gladden ML Jr, Gillingham BL, Hennrikus W, et al. Aneurysmal bone cyst of the first cervical vertebrae in a child treated with percutaneous intralesional injection of calcitonin and methylpred-nisolone. A case report. Spine 2000; 25(4)527–530.PubMedCrossRefGoogle Scholar
  3. 3.
    Galibert P, Deramond H, Rosat P, et al. [Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebro-plasty] Neurochirurgie 1987; 33(2):166–168.PubMedGoogle Scholar
  4. 4.
    Cardon T, Hachulla E, Flipo RM, et al. Percutaneous vertebroplasty with acrylic cement in the treatment of a Langerhans cell vertebral histiocytosis. Clin Rheumatol 1994; 13(3):518–521.PubMedCrossRefGoogle Scholar
  5. 5.
    Cotten A, Boutry N, Cortet B, et al. Percutaneous vertebroplasty: state of the art. Radiographics 1998; 18(2):311–323.PubMedGoogle Scholar
  6. 6.
    Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma. Analysis of 1000 autopsied cases. Cancer 1950; 3:74–85.PubMedCrossRefGoogle Scholar
  7. 7.
    Malawer MM, Delandy TF. Treatment of metastatic cancer to bone. In: De Vita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 3rd ed. Philadelphia: JB Lippincott Co; 1989: 2298–2317.Google Scholar
  8. 8.
    Bontoux D, Azais I. Cancer secondaire des os. Clinique et epidémiologic. In: Bontoux D, Alcalay M, eds. Cancer Secondaire des Os. Paris: Expansion Scientifique Française; 1997:19–27.Google Scholar
  9. 9.
    Tubiana-Hulin M. Incidence, prevalence and distribution of bone metastases. Bone 1991; 12(suppl 1):S9–S10.PubMedCrossRefGoogle Scholar
  10. 10.
    Tatsui H, Onomura T, Morishita S, et al. Survival rates of patients with metastatic spinal cancer after scintigraphic detection of abnormal radioactive accumulation. Spine 1996; 21(18):2143–2148.PubMedCrossRefGoogle Scholar
  11. 11.
    Deramond H, Depriester C, Toussaint P. [Vertebroplasty and percutaneous interventional radiology in bone metastases: techniques, indications, contra-indications.] Bull Cancer Radiother 1996; 83(4):277–282.PubMedCrossRefGoogle Scholar
  12. 12.
    Weill A, Chiras J, Simon JM, et al. Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement. Radiology 1996; 199(1):241–247.PubMedGoogle Scholar
  13. 13.
    Cotten A, Dewatre F, Cortet B, et al. Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up. Radiology 1996; 200(2)525–530.PubMedGoogle Scholar
  14. 14.
    Belkoff SM, Mathis JM, Jasper LE, et al. The biomechanics of vertebroplasty: the effect of cement volume on mechanical behavior. Spine 2001; 26(14):1537–1541.PubMedCrossRefGoogle Scholar
  15. 15.
    Lapras C, Mottolese C, Deruty R, et al. [Percutaneous injection of methylmethacrylate in osteoporosis and severe vertebral osteolysis (Galibert’s technic).] Ann Chir 1989; 43(5):371–376.PubMedGoogle Scholar
  16. 16.
    Kaemmerlen P, Thiesse P, Bouvard H, et al. [Percutaneous vertebroplasty in the treatment of metastases. Technic and results.] J Radiol 1989; 70(10)557–562.PubMedGoogle Scholar
  17. 17.
    Kaemmerlen P, Thiesse P, Jonas P, et al. Percutaneous injection of orthopedic cement in metastatic vertebral lesions [letter]. N Engl J Med 1989; 321(2):121.PubMedGoogle Scholar
  18. 18.
    Cortet B, Cotten A, Boutry N, et al. Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myeloma [see comments]. Rev Rhum Engl Ed 1997; 64(3): 177–183.PubMedGoogle Scholar
  19. 19.
    Deramond H, Wright NT, Belkoff SM. Temperature elevation caused by bone cement polymerization during vertebroplasty. Bone 1999; 25(2 suppl):17S-21S.PubMedCrossRefGoogle Scholar
  20. 20.
    San Millan RD, Burkhardt K, Jean B, et al. Pathology findings with acrylic implants. Bone 1999; 25(2 suppl):85S–90S.CrossRefGoogle Scholar
  21. 21.
    Chiras J, Depriester C, Weill A, et al. [Percutaneous vertebral surgery. Technics and indications.] J Neuroradiol 1997; 24(1):45–59.PubMedGoogle Scholar
  22. 22.
    Shepherd S. Radiotherapy and the management of metastatic bone pain. Clin Radiol 1988; 39(5)547–550.PubMedCrossRefGoogle Scholar
  23. 23.
    Salazar OM, Rubin P, Hendrickson FR, et al. Single-dose half-body irradiation for the palliation of multiple bone metastases from solid tumors: a preliminary report. Int J Radiat Oncol Biol Phys 1981; 7: 773–781.PubMedCrossRefGoogle Scholar
  24. 24.
    Murray JA, Bruels MC, Lindberg RD. Irradiation of polymethylmethacrylate. In vitro gamma radiation effect. J Bone Joint Surg 1974; 56A(2):311–312.Google Scholar
  25. 25.
    Riley LH, Frassica DA, Kostuik JP, et al. Metastatic disease to the spine: diagnosis and treatment. Instr Course Led 2000; 49:471–477.Google Scholar
  26. 26.
    Gangi A, Guth S, Dietemann JL, et al. Interventional musculoskeletal procedures. Radiographics 2001; 21(2)520.Google Scholar
  27. 27.
    Meder JF, Reizine D, Chiras J, et al. Apport de l’arthériographie dans le diagnostic et la traitement des tumeurs du rachis. Rachis 1992; 4(4):215–218.Google Scholar
  28. 28.
    Longo DL. Plasma cell disorders. In: Wilson JD, Braunwald E, Isselbacher KJ, et al., eds. Harrison’s Principles of Internal Mediane. 12th ed. New York: McGraw-Hill; 1991:1412–1416.Google Scholar
  29. 29.
    Bataille R, Chappard D, Klein B. Mechanisms of bone lesions in multiple myeloma. Hematol Oncol Clin North Am 1992; 6(2):285–295.PubMedGoogle Scholar
  30. 30.
    Lecouvet FE, Vande Berg BC, Maldague BE, et al. Vertebral compression fractures in multiple myeloma. Part I. Distribution and appearance at MR imaging [see comments]. Radiology 1997; 204(1):195–199.PubMedGoogle Scholar
  31. 31.
    Salmon SE, Cassady JR. Plasma cell neoplasms. In: De Vita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 4th ed. Philadelphia: JB Lippincott Co; 1993:1984–2025.Google Scholar
  32. 32.
    de Gramont A, Benitez O, Brissaud P, et al. Quantification of bone lytic lesions and prognosis in myelomatosis. Scand J Haematol 1985; 34(1):78–82.PubMedCrossRefGoogle Scholar
  33. 33.
    Kanis JA, McCloskey EV. Disorders of calcium metabolism and their management. In: Malpas JS, Bergsagel DE, Kyle RA, eds. Myeloma: Biology and Management. New York: Oxford University Press; 1995: 375–396.Google Scholar
  34. 34.
    Kapadia SB. Multiple myeloma: a clinicopathologic study of 62 consecutively autopsied cases. Medicine (Baltimore) 1980; 59(5):380–392.CrossRefGoogle Scholar
  35. 35.
    Kyle RA. Multiple myeloma: review of 869 cases. Mayo Clin Proc 1975; 50(1):29–40.PubMedGoogle Scholar
  36. 36.
    Carson CP, Ackerman LV, Maltby JD. Plasma cell myeloma: a clinical, pathologic, and roentgenologic review of 90 cases. Am J Clin Pathol 1955; 25:849–888.PubMedGoogle Scholar
  37. 37.
    Riccardi A, Gobbi PG, Ucci G, et al. Changing clinical presentation of multiple myeloma. Eur J Cancer 1991; 27(11):1401–1405.PubMedCrossRefGoogle Scholar
  38. 38.
    Spiess JL, Adelstein DJ, Hines JD. Multiple myeloma presenting with spinal cord compression. Oncology 1988; 45(2):88–92.PubMedCrossRefGoogle Scholar
  39. 39.
    Lecouvet FE, Malghem J, Michaux L, et al. Vertebral compression fractures in multiple myeloma. Part II. Assessment of fracture risk with MR imaging of spinal bone marrow [see comments]. Radiology 1997; 204(1):201–205.PubMedGoogle Scholar
  40. 40.
    Moulopoulos LA, Dimopoulos MA, Weber D, et al. Magnetic resonance imaging in the staging of solitary plasmacytoma of bone. J Clin Oncol 1993; 11(7):1311–1315.PubMedGoogle Scholar
  41. 41.
    Knowling MA, Harwood AR, Bergsagel DE. Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone. J Clin Oncol 1983; 1(4):255–262.PubMedGoogle Scholar
  42. 42.
    Chak LY, Cox RS, Bostwick DG, et al. Solitary plasmacytoma of bone: treatment, progression, and survival. J Clin Oncol 1987; 5(11):1811–1815.PubMedGoogle Scholar
  43. 43.
    Frassica DA, Frassica FJ, Schray MF, et al. Solitary plasmacytoma of bone: Mayo Clinic experience. Int J Radiat Oncol Biol Phys 1989; 16(1): 43–18.PubMedCrossRefGoogle Scholar
  44. 44.
    Dimopoulos MA, Goldstein J, Fuller L, et al. Curability of solitary bone plasmacytoma. J Clin Oncol 1992; 10(4)587–590.PubMedGoogle Scholar
  45. 45.
    Holland J, Trenkner DA, Wasserman TH, et al. Plasmacytoma. Treatment results and conversion to myeloma. Cancer 1992; 69(6): 1513–1517.PubMedCrossRefGoogle Scholar
  46. 46.
    Murphy KJ, Deramond H. Percutaneous vertebroplasty in benign and malignant disease. Neuroimaging Clin North Am 2000; 10(3):535–545.Google Scholar
  47. 47.
    Deramond H, Depriester C, Galibert P, et al. Percutaneous vertebroplasty with polymethyl methacrylate. Technique, indications, and results. Radiol Clin North Am 1998; 36(3)533–546.PubMedCrossRefGoogle Scholar
  48. 48.
    Huvos AG. Multiple myeloma including solitary osseous myeloma. In: Bone Tumors: Diagnosis, Treatment, and Prognosis. Philadelphia: WB Saunders Co; 1992:653–676.Google Scholar
  49. 49.
    Plowman PN. Radiotherapy of myeloma. In: Malpas JS, Bergsagel DE, Kyle RA, eds. Myeloma: Biology and Management. New York: Oxford University Press; 1995:314–321.Google Scholar
  50. 50.
    Lecouvet F, Richard F, Van de Berg B, et al. Long-term effects of localized spinal radiation therapy on vertebral fractures and focal lesions appearance in patients with multiple myeloma. Br J Haematol 1997; 96(4):743–745.PubMedCrossRefGoogle Scholar
  51. 51.
    Hoskin PJ. Radiotherapy in the management of bone pain. Clin Orthop 1995; 312:105–119.PubMedGoogle Scholar
  52. 52.
    Schmorl G, Junghanns H. The Human Spine in Health and Disease (Besemann ES, transl. and ed.). 2nd ed. New York: Grune & Strat-ton; 1971.Google Scholar
  53. 53.
    Laredo JD, Assouline E, Gelbert F, et al. Vertebral hemangiomas: fat content as a sign of aggressiveness. Radiology 1990; 177(2):467–472.PubMedGoogle Scholar
  54. 54.
    Laredo JD, Reizine D, Bard M, et al. Vertebral hemangiomas: radiologic evaluation. Radiology 1986; 161(1):183–189.PubMedGoogle Scholar
  55. 55.
    Ware JE, Jr., Snow KK, Kosinski M, et al. SF-36 Health Survey. Manual and Interpretation Guide. Boston: The Health Institute; 1993.Google Scholar
  56. 56.
    Deramond H, Darrason R, Galibert P. [Percutaneous vertebroplasty with acrylic cement in the treatment of aggressive spinal angiomas.] Rachis 1989; 1(2):143–153.Google Scholar
  57. 57.
    Cotten A, Deramond H, Cortet B, et al. Preoperative percutaneous injection of methyl methacrylate and N-butyl cyanoacrylate in vertebral hemangiomas. Am J Neuroradiol 1996; 17(1):137–142.PubMedGoogle Scholar
  58. 58.
    Heiss JD, Doppman JL, Oldfield EH. Brief report: relief of spinal cord compression from vertebral hemangioma by intralesional injection of absolute ethanol [see comments]. N Engl J Med 1994; 331(8):508–511.PubMedCrossRefGoogle Scholar
  59. 59.
    Heiss JD, Doppman JL, Oldfield EH. Treatment of vertebral hemangioma by intralesional injection of absolute ethanol [letter; comment]. N Engl J Med 1996; 334(20):1340.PubMedCrossRefGoogle Scholar
  60. 60.
    Gangi A, Kastler BA, Dietemann JL. Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. Am J Neuroradiol 1994; 15(1):83–86.PubMedGoogle Scholar
  61. 61.
    Ide C, Gangi A, Rimmelin A, et al. Vertebral haemangiomas with spinal cord compression: the place of preoperative percutaneous vertebroplasty with methyl methacrylate. Neuroradiology 1996; 38(6): 585–589.PubMedCrossRefGoogle Scholar
  62. 62.
    Martin JB, Jean B, Sugiu K, et al. Vertebroplasty: clinical experience and follow-up results. Bone 1999; 25(2 suppl):11S–15S.PubMedCrossRefGoogle Scholar
  63. 63.
    Craig FS. Vertebral-body biopsy. J Bone Joint Surg 1956; 38A(1):93–102.Google Scholar
  64. 64.
    Yang ZY, Zhang LJ, Chen ZX, et al. Hemangioma of the vertebral column. A report on twenty-three patients with special reference to functional recovery after radiation therapy. Acta Radiol Oncol 1985; 24(2):129–132.PubMedCrossRefGoogle Scholar
  65. 65.
    Pavlovitch JM, Nguyen JP, Djindjian M, et al. Radiotherapy of compressive vertebral hemangiomas. Neurochirurgie 1989; 35:296–298.PubMedGoogle Scholar
  66. 66.
    Nguyen JP, Djindjian M, Pavlovitch JM, et al. Vertebral hemangiomas with neurologic symptoms. Treatment. Results of the “Société Française de Neuro-Chirurgie” series. Neurochirurgie 1989; 35: 299–303.PubMedGoogle Scholar
  67. 67.
    Nguyen JP, Djindjian M, Gaston A, et al. Vertebral hemangiomas presenting with neurologic symptoms. Surg Neurol 1987; 27(4):391–397.PubMedCrossRefGoogle Scholar
  68. 68.
    Nguyen JP, Djindjian M, Badiane S. Vertebral hemangiomas with neurologic symptoms. Clinical presentation. Results of the “Société Française de Neurochirurgie” series. Neurochirurgie 1989; 35:270–274.PubMedGoogle Scholar
  69. 69.
    Picard L, Bracard S, Roland J, et al. [Embolization of vertebral hemangioma. Technic-indications-results.] Embolisation des hemangiomes vertebraux. Technique-indications-resultats. Neurochirurgie 1989; 35(5):289–293.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Hervé Deramond
  • Claude Depriester
  • Jacques Chiras
  • Anne Cotten
  • Nathalie Boutry
  • Bernard Cortet

There are no affiliations available

Personalised recommendations