Differential Gene Expression of Tyrosine Hydroxylase in Rats Exposed Long-Term to Various Stressors

  • Richard Kvetnansky
  • Bistra B. Nankova
  • Milan Rusnak
  • Lucia Micutkova
  • Lucia Kubovcakova
  • Sladjana Dronjak
  • Olga Krizanova
  • Esther L. Sabban
Part of the Advances in Behavioral Biology book series (ABBI, volume 53)

Abstract

Activity of the sympathetic-adrenomedullary system (SAS) in rats exposed to heterotypic novel stressors after prior chronic stress exposure is poorly understood. A potentiation of SAS activity evaluated by plasma catecholamine levels in chronically stressed rats exposed to novel stressors has been reported (Dronjak et al., 2001). The exaggerated effect of novel stressors is an interesting phenomenon, but its mechanism at the level of adrenomedullary gene expression of catecholamine biosynthetic enzymes is not known.

Keywords

Tyrosine Hydroxylase Adrenal Medulla Immobilization Stress Plasma Catecholamine Level Tyrosine Hydroxylase mRNA 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Richard Kvetnansky
    • 1
  • Bistra B. Nankova
    • 2
  • Milan Rusnak
    • 1
  • Lucia Micutkova
    • 1
  • Lucia Kubovcakova
    • 1
  • Sladjana Dronjak
    • 1
  • Olga Krizanova
    • 1
  • Esther L. Sabban
    • 2
  1. 1.Institute of Experimental EndocrinologySlovak Academy of SciencesBratislavaSlovak Republic
  2. 2.New York Medical CollegeValhallaUSA

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