Differential Regulation of Myocardial Cell Apoptosis by α- and β-Adrenergic Pathways

  • Koji Hasegawa
  • Eri Iwai-Kanai
  • Shigetake Sasayama
Part of the Advances in Behavioral Biology book series (ABBI, volume 53)

Abstract

The apoptosis of cardiac myocytes may play a role in the development of heart failure.1–3 Norepinephrine is one of factors activated in heart failure4 and can induce myocardial cell apoptosis in culture.5 However, it is unknown if α- and β-adrenergic pathways coordinately or differentially regulate apoptosis and if this apoptotic pathway utilizes common or cell type-specific apoptotic signals.

Keywords

Cardiac Myocytes Brain Natriuretic Peptide Atrial Natriuretic Peptide Adrenergic Pathway PCI2 Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Koji Hasegawa
    • 1
  • Eri Iwai-Kanai
    • 1
  • Shigetake Sasayama
    • 1
  1. 1.Department of Cardiovascular Medicine, Graduate School of MedicineKyoto UniversityKyotoJapan

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