Effect of Chronic Ischemia on Human Small Arteries

  • C. Hillier
  • R. D. Sayers
  • P. A. C. Watt
  • P. R. F. Bell
  • H. Thurston
Part of the Experimental Biology and Medicine book series (EBAM, volume 26)

Abstract

Critical limb ischemia (CLI) is the term used to describe chronic ischemia which is of a severity to endanger the whole or part of the leg. It is generally caused by advanced atherosclerotic peripheral vascular disease producing an occlusion of a large artery or arteries in the leg. The hemodynamic consequences are increased resistance at the proximal obstruction with a reduction in distal perfusion pressure and blood flow to the peripheral circulation (1).

Keywords

Nitric Oxide Small Artery Chronic Ischemia Concentration Response Curve Small Resistance Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • C. Hillier
    • 2
  • R. D. Sayers
    • 2
    • 1
  • P. A. C. Watt
    • 2
  • P. R. F. Bell
    • 2
    • 1
  • H. Thurston
    • 2
  1. 1.Departments of Medicine and SurgeryUniversity of LeicesterLeicesterEngland
  2. 2.Clinical Sciences BuildingLeicester Royal InfirmaryLeicesterEngland

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