Blood Flow in Skeletal Muscle
With the development of laser-Doppler flowmetry (LDF) (see chapters 1, 2), a new field has opened for quantitative studies of microvascular perfusion in various tissues. LDF allows quick, continuous, and noninvasive assessments of microvascular flow, both in clinical practice and in laboratory animal research. The potential benefits of LDF for the advancement of cardiovascular science have attracted considerable attention among researchers, who have already provided a variety of new insights and applications for this emerging technology. This chapter outlines the applications of LDF for studies of the skeletal muscle circulation. It summarizes existing studies of the skeletal muscle circulation using LDF, and focuses in detail upon comparisons of laser-Doppler flowmeter signals with independent measures of microvascular flow. The final section of the chapter illustrates several new applications of LDF for the study of blood flow in skeletal muscle.
KeywordsMuscle Blood Flow Gracilis Muscle Tissue Blood Flow Microvascular Perfusion Inferior Epigastric Artery
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- 1.Holmstrom, A., and D.H. Lewis. 1983. Regional blood flow in skeletal muscle after high-energy trauma. Acta Chir Scand 145:453–458.Google Scholar
- 2.Lewis, D. H., A. Holmstrom, G.E. Nilsson, T. Tenland, P. Å. Oberg, and J. Larsson. 1979. Skeletal muscle trauma: Correlation of microcirculatory and biochemical changes. Microvasc Res 18:286 (abstract).Google Scholar
- 3.Nicholson, C. D. 1984. Blood cell flux in the gastrocnemius muscle of the anesthetized rat. Int J Microcirc Clin Exp 3:433 (abstract).Google Scholar
- 5.Öberg, P. Å., G.E. Nilsson, T. Tenland, A. Holmstrom, and D.H. Lewis. 1979. Measurement of skeletal muscle blood flow in bullet wounding with a new laser-Doppler flowmeter. Microvasc Res 18:298 (abstract).Google Scholar
- 16.Gush, R.J., T.A. King, and M.I.V. Jayson. 1984. In vivo measurement of subcutaneous and intramuscular tissue blood flow by a laser-Doppler microprobe. Int J Microcirc Clin Exp 3:433 (abstract).Google Scholar