Some Considerations on Critical Concentration of Cadmium for Renal Toxicity in Rats

  • Chiharu Tohyama
  • Naoko Sugihira
  • Kazuo T. Suzuki
  • Masataka Murakami
  • Hiroshi Saito

Abstract

Cadmium (Cd) is a widespread toxic environmental pollutant. Environmental and occupational exposure results in the accumulation of this metal particularly in the liver and kidney and during the life-long exposure a renal Cd concentration becomes higher than a hepatic Cd concentration, which often causes renal tubular dysfunction (Friberg et al., 1985). Thus, we need to know the critical concentration of Cd to obtain information on the safety margin of exposure to this metal and the allowable daily intake levels.

Keywords

Critical Concentration Renal Cortex Renal Toxicity Hepatic Damage Renal Tubular Dysfunction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Chiharu Tohyama
    • 1
  • Naoko Sugihira
    • 1
  • Kazuo T. Suzuki
    • 1
  • Masataka Murakami
    • 1
  • Hiroshi Saito
    • 1
  1. 1.Environmental Health Sciences DivisionNational Institute for Environmental StudiesOnogawa, Yatabe-machi, Tsukuba, Ibaraki 305Japan

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