Tubulin as a G-Protein: Regulation of Tubulin-Tubulin Interactions by GTP Hydrolysis
As proposed by Hughes in 19831, tubulin belongs to, the large family of GTP-binding proteins, which contains several other subclasses: the elongation and initiation factors of protein synthesis, and proteins involved in signal transduction such as G , G., transducin and the Ras p21 proteins ; recently this family has Deen extended to include low molecular weight YPTl and SEC4 proteins involved in the regulation of secretion (for a review see reference 2).
KeywordsDynamic Instability Aluminum Fluoride Tubulin Subunit SEC4 Protein Microtubule Dynamic Instability
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