Transduction is the term used to designate the bacteriophage-mediated transfer of DNA from one cell (a donor) to another cell (a recipient). It was first described by Zinder and Lederberg for Salmonella and phage P22 but has since been shown to occur in many other bacteria and to involve a variety of bacteriophages. Depending on which virus is involved, the donor cell DNA may or may not be associated with viral DNA inside the capsid of the bacteriophage. However, in all cases of transduction it is necessary for the donor cell to lyse and for the virions carrying host DNA (the transducing particles) to be capable of injecting their DNA into a new cell. A cell that has acquired a recombinant phenotype by this process is called a transductant.
KeywordsGeneralize Transduce Temperate Phage Helper Phage Transduce Phage Transduce Particle
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