Renal Transplantation Combined with Pancreas Transplantation: Is There a Clinical Indication?
Part of the Topics in Renal Medicine book series (TIRM, volume 6)
Most pancreas transplantations are currently made either simultaneously with a kidney transplant or after a successful kidney transplantation [1–3]. In the latter instance, a pancreas from a living related pancreas donor has in some cases been used . Kidney transplantation, if possible before dialysis, is the treatment of choice for terminal diabetic nephropathy [4–6]. If we are to combine this therapy with a pancreas transplantation, the following conditions must be fulfilled:
Patient and kidney graft survival must not be jeopardized
The pancreas graft must have a reasonable success rate
The procedure must give improved quality of life and/or improved prognosis
KeywordsDiabetic Nephropathy Proliferative Diabetic Retinopathy Pancreas Transplantation Live Donor Kidney Live Donor Kidney Transplantation
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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- 2.Brekke I, Dyrbekk D, Jakobsen A, Jervell J, Social G, Flatmark A: Combined pancreas and kidney transplantation for diabetic nephropathy. Transplant Proc 18: 63–64, 1986.Google Scholar
- 3.Traeger J, Dubernard JM, Bosi E, Secchi A, Gelet A, El Yafi S, Touraine JL, Pontiroli AE, Pozza G: Human segmental pancreatic transplantation for the treatment of insulin-dependent diabetes. In: Keen H, Legrain M (eds) Prevention and treatment of diabetic nephropathy. Lancester UK: MTP Press, 1983 pp 221–228.Google Scholar
- 5.Jervell J, Brekke I, Fauchald P, Flatmark A: Management of diabetic renal failure. In: Nattrass M. (ed) Recent advances in diabetes, vol 2. Edinburgh: Churchill Livingstone, 1986, pp 151–162.Google Scholar
- 7.Dubernard JM, Traeger J, Bosi E, Gelet A, El Yafi S, Secchi A, Piatti PM, Ruitton AM, Touraine JL, Pozza G: The technique of neoprene injection for human pancreatic transplantation: experience in 40 cases. Transplant Proc 16: 684–686, 1984.Google Scholar
- 8.Kampik A, Ultig M: Is proliferative diabetic retinopathy an indication for pancreatic transplantation. Transplant Proc [Suppl 3] 18: 62–63, 1986.Google Scholar
© Springer Science+Business Media Dordrecht 1988