Characterization of Isolated Cells in Primary Culture from Human term Placenta by Electron Microscopy and Immunohistochemistry

  • Juliet O. Lobo
  • Francis L. Bellino
  • Alan Siegel
Part of the Trophoblast Research book series (TR)


During pregnancy the syncytiotrophoblast layer of the human placenta elaborates both protein and steroid hormones (Gaspard et al., 1980; Simpson and MacDonald, 1981; Winkel et al., 1980). The mitotically inactive but biochemically functional syncytiotrophoblasts are formed in vivo by the fusion of the underlying mitotically active, mature, mononucleated cytotrophoblast cells (Boyd and Hamilton, 1967; Enders, 1965; Pierce and Midgley, 1963; Wislocki and Dempsey, 1955; Wynn, 1972).


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Juliet O. Lobo
    • 1
  • Francis L. Bellino
    • 1
  • Alan Siegel
    • 1
  1. 1.Dept. of Biological SciencesState University of New York at BuffaloBuffaloUSA

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