The Association of Mixed Lymphocyte Reaction (MLR) Blocking Factors and Maternal Antipaternal Leukocytotoxic Antibodies with Pregnancy Outcome in Women with Recurrent Abortions Immunized with Paternal or Third Party Leukocytes

  • Alan E. Beer
  • James F. Quebbeman
  • A. Enrico Semprini
  • Zhu Xiaoyu
Part of the Trophoblast Research book series (TR)


Our recent investigations have been directed toward analyzing an immunogentic basis for recurrent idiopathic spontaneous abortions in human couples (Beer et al., 1985). We have limited our study to couples who were evaluated medically, genetically, microbiologically, and structurally as previously reported by us and were found to lack any etiology known to be associated with recurrent pregnancy losses (Beer et al., 1983). All couples had an immunogenetic work up as outline in Table 1. The materials and methods utilized in this study have been reported previously (Beer et al., 1981).


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Alan E. Beer
    • 1
  • James F. Quebbeman
  • A. Enrico Semprini
    • 2
  • Zhu Xiaoyu
    • 3
  1. 1.Department of Obstetrics and GynecologyUniversity of MichiganAnn ArborUSA
  2. 2.University of MilanoMilanoItaly
  3. 3.Wuhan, HubeiPeople’s Republic of China

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