Effects of Lecithin on Memory and Learning
The effects of cholinergic agonists and antagonists on mnestic performance has been documented by a variety of experimental studies with animals and human beings. A summary on this topic was published by Drachman & Sahakian in 1979. These studies seem to substantiate the theory of a performance impairing effect of cholinergic antagonists, whereas a hypothesis of a memory supporting function of cholinergic agonists currently lacks empirical support and is based only on theoretical assumptions. Mainly for patients with presenile and senile dementia it could be demonstrated that mnestic impairment can be decreased by choline, physostigmine and lecithin (Etienne et al., 1979; Vroulis et al., 1981; Tweedy & Garcia, 1982; Wood & Allison, 1982; Johns et al., 1983 and Thal et al., 1983). On the other hand, Christie et al. (1979) report that lecithin had no effect on the memory performances of 12 patients with Morbus Alzheimer and only for a very few patients a tendency toward improved performance was observable.
KeywordsVerbal Memory Senile Dementia Cholinergic Agonist Cholinergic Antagonist Choline Metabolism
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