Cardiology pp 391-409 | Cite as

Platelet Spreading and Thrombi-Formation in Vitro

  • V. Leytin
  • S. Domogatsky
  • V. Koteliansky
  • A. Mazurov
  • F. Misselwitz
  • O. Merzlikina
  • E. Podrez
  • K. Taube
  • W. Forster

Abstract

The present paper deals with three main problems. In the first section we consider platelet interaction with surfaces coated with genetically distinct types of human collagen, which makes a part of various vessel wall structures. The main stages of plateletscollagenous substrates interaction are described: a) initial attachment of platelets to the substrate, b) platelet spreading on the substrate, and c) formation of thrombi-like aggregates adherent to the substrate.

Keywords

Arachidonic Acid Collagen Substrate Radial Spreading Human Collagen Induce Platelet Aggregation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • V. Leytin
    • 1
  • S. Domogatsky
    • 1
  • V. Koteliansky
    • 1
  • A. Mazurov
    • 1
  • F. Misselwitz
    • 1
  • O. Merzlikina
    • 1
  • E. Podrez
    • 1
  • K. Taube
    • 2
  • W. Forster
    • 2
  1. 1.USSR Cardiology Research CenterAcademy of Medical SciencesMoscowUSSR
  2. 2.Institute of Pharmacology and Toxicology of MartinLuther UniversityHalle-Wittenberg, HalleGermany

Personalised recommendations