Alkylation of Nucleophilic Carbon. Enolates and Enamines

  • Francis A. Carey
  • Richard J. Sundberg
Part of the Advanced Organic Chemistry book series

Abstract

Since practically all syntheses of any complexity involve carbon—carbon bondforming steps as an essential feature, the availability of methods which allow two molecular fragments to be connected by the reaction of a nucleophilic carbon with an electrophilic one can be crucial to the success of a synthetic plan. The emphasis in this chapter is on enolate ions and enamines, two of the most useful kinds of carbon nucleophiles, their preparation, and their reactions with alkylating agents. Certain related nucleophilic carbon species will also be discussed.

Keywords

Ethyl Acetoacetate Conjugate Addition Lithium Diisopropylamide Enolate Anion Enol Acetate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Francis A. Carey
    • 1
  • Richard J. Sundberg
    • 1
  1. 1.University of VirginiaCharlottesvilleUSA

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