T4 Bacteriophage as a Model Genetic System
This chapter, in combination with Chapters 5 and 6, will present an overview of some of the most extensively studied bacteriophages. The intent of all three chapters is to illustrate the basic nature of genetic processes using some of the simplest genetic systems as examples. In Chapter 1, the distinction was made between phages which are always virulent and those which can temper their lytic response to form lysogens. Chapters 4 and 5 will discuss the intemperate (i.e., virulent) phages, while Chapter 6 will discuss the problems associated with lysogeny. The details concerning regulation of the kinds of metabolic activities discussed in these chapters will be deferred until Chapter 12.
KeywordsPhage Particle Phage Infection Tail Fiber Hydroxymethyl Cytosine Eclipse Phase
Unable to display preview. Download preview PDF.
- Rabussay, D., Geiduschek, E.P. 1977. Regulation of gene action in the development of lytic bacteriophages, pp. 1–196. In: Fraenkel-Conrat, H., Wagner, R.R. (eds.) Comprehensive Virology, vol. 8. New York: Plenum Press.Google Scholar
- Wu, R., Geiduschek, E.P., Rabussay, D., Cascino, A. 1973. Regulation of transcription in bacteriophage T4-infected E. coli—A brief review and some recent results, pp. 181–204. In: Fox, C.F., Robinson, W.S. (eds.) Virus Research. New York: Academic Press.Google Scholar
- Wood, W.B., King, J. 1979. Genetic control of complex bacteriophage assembly, pp. 581–635. In: Fraenkel-Conrat, H., Wagner, R.R. (eds.) Comprehensive Virology vol. 13. New York: Plenum Press.Google Scholar