The Effect of Weight Reduction on Urate Metabolism
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The common view of the etiology of gout has related it to obesity and over-indulgence in food. Contrariwise, gout was seen much less frequently in undernourished European countries during World War II. Our observations of patients with primary gout have shown that many weigh considerably more than their desirable weight for height (1). Little is understood however, concerning possible pathogenetic mechanisms involved in this association. One approach would be to characterize urate metabolism in an obese subject who had suffered from gout and then to define it on a second occasion by an identical technique after he had lost weight.
KeywordsWeight Reduction Obese Subject Serum Urate Gouty Arthritis Serum Urate Concentration
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