The Use of High Pressure Liquid Chromatography to Monitor Nucleotide Levels in Cells

  • Phyllis R. Brown
  • R. E. ParksJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 41 B)

Abstract

High pressure liquid chromatography has proved to be a valuable tool in measuring the nucleotide levels in cell extracts (1, 2). The analyses are accomplished with high speed, sensitivity, resolution and accuracy. A decided advantage of this technique is that the major naturally occurring nucleotides can be monitored at one time concurrently with nucleotides of purine and pyrimidine analogs.

Keywords

High Pressure Liquid Chromatography Adenine Nucleotide Anion Exchange Resin Purine Analog Pyrimidine Analog 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • Phyllis R. Brown
    • 1
  • R. E. ParksJr.
    • 1
  1. 1.Division of Biological and Medical SciencesBrown UniversityProvidenceUSA

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