Receptors and Aging

  • Gerald D. Hess
  • George S. Roth

Abstract

Recent years have seen major advances in neuroendocrinology, neurobiology, and membrane biochemistry. Hormone and neurotransmitter receptors were poorly understood and many were unknown until a few years ago. During the past decade there has been a growing realization that neurotransmitters convey nerve impulses and that hormone receptors ultimately convey “messages” to cellular control centers (Pradham, 1980; Cuatrecases, 1974). While some researchers have attempted to document the age-related deterioration of physiological control systems in a general way, this study considers the role of hormone and neurotransmitter receptors in the age-related dysfunctions of once “finely tuned” control systems. Current studies of age changes in receptors come from such diverse fields as pharmacology, neuroendocrinology, and experimental psychology. These and related subdisciplines are becoming increasingly aware of the importance of such studies viewed from a gerontological perspective.

Keywords

Androgen Receptor Glucocorticoid Receptor Ergot Alkaloid Opiate Receptor Corpus Striatum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • Gerald D. Hess
    • 1
  • George S. Roth
    • 2
  1. 1.Department of Natural SciencesMessiah CollegeGranthamUSA
  2. 2.National Institute on Aging, National Institutes of Health, Gerontology Research CenterBaltimore City HospitalsBaltimoreUSA

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