The Genesis of Cortical Event-Related Potentials: Excitatory and Inhibitory Contributions

  • Herbert G. VaughanJr.
  • Charles E. Schroeder
  • Joseph C. Arezzo
Part of the Brain Dynamics book series (BD)

Abstract

Event-related potentials (ERPs) provide the principal real-time index of neural processes involved in the sensorimotor and cognitive operations of the human brain. The value of ERPs for investigating human brain mechanisms has been limited by our lack of information concerning the anatomic location of their intracranial generators and the physiologic processes underlying individual ERP components. Recent advances in the analysis of topographic data, such as Brain Electrical Source Analysis or BESA (Scherg, 1990; Scherg and Picton, 1991), however, facilitated the localization and definition of the time course of activity within each active brain region. BESA, in conjunction with magnetic resonance imaging, has been successfully utilized to demonstrate retinotopic localization of ERPs in striate cortex (Mehta et al., 1990) and the sequential activation of visual cortical areas involved in pattern and spatial discrimination tasks (Simpson et al., 1990). The ability to define the temporal features of activity within specific brain structures of humans highlights the importance of clarifying the neural mechanisms that underlie these slow field potentials at the cellular level.

Keywords

Visual Evoke Potential Auditory Evoke Potential Current Source Density Current Sink Excitatory Process 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Herbert G. VaughanJr.
  • Charles E. Schroeder
  • Joseph C. Arezzo

There are no affiliations available

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