A Study of Granuloma Formation by Molluscan Cells
The development, nature, and functional significance of infectious granulomatoses in mammals, particularly humans, have held a position of central interest in immunopathology for decades. First recognized in patients who had died from tuberculosis, these inflammatory cellular aggregat es, referred to as “tub ercules,” were identified as being comprised of large phagocytic cells or hist iocytes. Furthermore, a prominent feature of each granuloma is the formation of multinucleated giant cells, containing a peripheral zone of lymphocytes, with or without plasma cells.
KeywordsAcid Phosphatase Acid Phosphatase Activity Granuloma Formation Sodium Fluoride Lead Nitrate
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