Assessing the Effects of Drugs on Ventilation/Perfusion
The lung is usually thought of as a passive window for metabolic gas exchange but, of course, this is not exactly so, as there is an active and constantly adjusted matching of ventilation to perfusion and vice-versa. Sometimes the processes become hyperactive, for example in asthma or pulmonary hypertension, and at other times they become weakened by disease as in emphysema or multiple micro-embolization. They can also be modified by treatment. However, it is by no means easy to measure or express these effects, when they influence more than one aspect of lung function at the same time.
KeywordsTotal Lung Capacity Tracheal Stenosis Airway Conductance Extrinsic Allergic Alveolitis Single Breath Carbon Monoxide
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