Monoaminergic Systems in the Human Limbic Brain

  • I. J. Farley
  • K. S. Price
  • O. Hornykiewicz

Abstract

There exist several reports in the literature on the distribution of serotonin (5-HT), dopamine (DA) and noradrenaline (NA) in the limbic system of laboratory animals (Paasonen et al, 1957; Brownstein et al, 1974; Saavedra et al, 1974). In addition to these reports, which are based on chemical analyses of the brain monoamines in question, there exists a wealth of pertinent information obtained by means of the histofluorescence technique for the visualization of monoamines in brain tissue (Dahlström & Fuxe, 1964; Fuxe, 1965; Lindvall & Bjorklund, 1974). However, to our knowledge, there exist no systematic biochemical studies of the monoamine levels in limbic areas of the human brain. This report deals with the distribution of 5-HT, DA and NA in limbic areas of the neurologically normal human brain, thus providing a suitable framework for future studies on the behaviour of these monoamines in the limbic brain of patients with neurological and/or psychiatric illnesses.

Keywords

Nucleus Accumbens Basal Forebrain Limbic Area Mammillary Body MONOAMINERGIC System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 1978

Authors and Affiliations

  • I. J. Farley
  • K. S. Price
  • O. Hornykiewicz

There are no affiliations available

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