Isolating tumour suppressor genes relevant to ovarian carcinoma — the role of loss of heterozygosity

  • W. D. Foulkes
  • J. Trowsdale


Despite the increasing use of chemotherapeutic regimens that achieve high rates of response, the long term outlook for patients with ovarian carcinoma remains dismal. The all-stage five year survival is about 28% and has not improved in the last decade or more [1]. It has become clear that new strategies are required and uncovering genes whose aberrant function can be demonstrated in ovarian carcinoma may have important diagnostic and therapeutic implications.


Ovarian Cancer Ovarian Carcinoma Retinitis Pigmentosa Human Ovarian Cancer Frequent Loss 
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© Chapman & Hall 1995

Authors and Affiliations

  • W. D. Foulkes
  • J. Trowsdale

There are no affiliations available

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