Eicosanoids and Cancer
There are many interesting and potentially important relationships between prostaglandins and various aspects of cancer. Associations have been found regarding cancer development, spread, host defense mechanisms and survival, etc. These factors are obviously relevant to the understanding of the initiation and progress of the disease. In addition, they are of more immediate relevance regarding the effects on cancer of common drugs such as aspirin and corticosteroids that alter prostaglandin metabolism or release. However, since there are so many processes involved, so many different types of cancer, and numerous prostaglandins, it is to be expected that the relationships are complex and often disputed.
KeywordsProstaglandin Synthesis Fatty Acid Derivative Lipoxygenase Product Prostaglandin Synthesis Inhibitor Tetradecanoyl Phorbol Acetate
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- 1.Bennett A. Prostaglandins and cancer. In: Practical Applications of Prostaglandins and their Synthesis Inhibitors. Ed. SMM Karim, Lancaster, MTP Press 1979; 149–88.Google Scholar
- 5.Bennett A. Prostaglandins and inhibitors of their synthesis in cancer growth and spread. In: Endocrinology of Cancer, Vol. 3, Ed. DP Rose, Florida, CRC Press 1982: 113–27.Google Scholar
- 6.Bennett A. Prostaglandins and cancer. In : Handbook of the Eicosanoids. Ed. AL Willis, B Vickery, C Pace-Asciak. Florida, CRC Press, in press.Google Scholar
- 7.Prostaglandins and Cancer: First International Conference. Ed. TJ Powles, RS Bockman, KV Honn et al, New York, Alan R. Liss, 1982.Google Scholar
- 8.Icosanoids and Cancer. Ed. H Thaler-Dao, A Crastes de Paulet, R Paoletti, New York, Raven Press, 1984.Google Scholar