Role of the Central Nervous System in The Control of Reproductive Mechanisms By Gonadal Steroids

  • Julian M. Davidson


Modification of gonadotropin secretion is the principal means whereby the oral contraceptive agents control fertility, and their natural counterparts - the ovarian hormones - regulate the reproductive cycle. Estrogenic steroids have inhibitory or “negative feedback” effects on the secretion of FSH and LH; progestins have a similar relationship to LH. Under certain circumstances both types of steroid can have stimulatory (“positive feedback”) effects on LH secretion. Synergistic relationships have been demonstrated between the inhibitory effects of the two ovarian steroids (1).


Luteinizing Hormone Gonadal Steroid Feedback Action Ovarian Steroid Cyproterone Acetate 
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Copyright information

© Plenum Press, New York 1969

Authors and Affiliations

  • Julian M. Davidson
    • 1
  1. 1.Department of PhysiologyStanford University Medical SchoolCaliforniaUSA

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