The Role of Progestins and Progesterone in Brain Function and Behavior

  • Bert S. Kopell


The extensive use of synthetic progestins as components of contraceptive preparations has focused interest on the effects of these substances on the central nervous system and on behavior. Recently the effects of progesterone and its metabolites on behavior has been reviewed by Hamburg (1), who emphasized that major clinical problems often occur during the postpartum period, the premenstrual period and menopause. These are periods of not only profomd psychological meaning to the woman but also periods of dramatic changes in the levels of circulating sexual hormones, in general, and progesterone, in particular.


Sexual Behavior Reticular Formation Seizure Threshold Paradoxical Sleep Hypothalamic Neuron 
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Copyright information

© Plenum Press, New York 1969

Authors and Affiliations

  • Bert S. Kopell
    • 1
  1. 1.Department of PsychiatryStanford University School of MedicineUSA

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