Longitudinal Studies of the Effects of Oral Contraceptive Therapy on Plasma Glucose, Non-Esterified Fatty Acid, Insulin and Blood Pyruvate Levels During Oral and Intravenous Glucose Tolerance Tests

  • V. Wynn
  • J. W. H. Doar


Relative impairment of oral and intravenous glucose tolerance has been found in certain women receiving oestrogen-progestagen combinations (1–6). In a cross-sectional study of 105 women taking oral contraceptives we found 18% of oral and 15% of intravenous glucose tolerance tests to be abnormal (2). Changes of circulating levels of other compounds related to glucose tolerance, including insulin (5–7), non-esterified fatty acid (NEFA) (2) and pyruvate (2) have also been noted by various investigators.


Glucose Tolerance Oral Contraceptive Plasma Glucose Level Versus Versus Versus Versus Plasma Insulin Level 
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Copyright information

© Plenum Press, New York 1969

Authors and Affiliations

  • V. Wynn
    • 1
  • J. W. H. Doar
    • 1
  1. 1.Alexander Simpson Laboratory for Metabolic ResearchSt. Mary’s Hospital Medical SchoolLondonUK

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