Coronaviruses pp 551-557 | Cite as

Stratagies for a Successful Coronavirus (TGE) Vaccine for Swine

  • C. Joseph Welter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 218)


Transmissible gastroenteritis (TGE) is a coronaviral enteric disease in swine responsible for substantial economic loss to the swine industry. Fifteen percent of nursing piglet diarrheas in the Midwestern States can be attributed to TGE.1 The natural route of infection is oral, with viral replication occuring in the small intestine, and leading to watery diarrhea, rapid dehydration and death of piglets under two weeks of age. Viremia and other localized infections do not appear to be prevalent during the course of the disease although infectious virus has been isolated from the lungs of clinically normal adult pigs.2


Passive Immunity Oral Vaccine Oral Vaccination Substantial Economic Loss Unvaccinated Control 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • C. Joseph Welter
    • 1
  1. 1.Ambico, Inc.Dallas CenterUSA

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