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Coronaviruses pp 123-129 | Cite as

Deduced Amino Acid Sequence and Potential O-Glycosylation Sites for the Bovine Coronavirus Matrix Protein

  • William Lapps
  • Brenda G. Hogue
  • David A. Brian
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 218)

Abstract

The nucleotide sequence of the matrix (M) protein gene of the bovine coronavirus (BCV) was determined by sequencing cDNA clones derived from genomic RNA. The gene was found to map at the 5′ side of the nucleocapsid protein gene and its sequence predicts a protein of 230 amino acids having a molecular weight of 26,376. The BCV M protein shares extensive sequence homology with the matrix protein of the mouse hepatitis coronavirus (MHV) but differs notably in the amino terminal region external to the virion envelope where BCV apparently uses at least two of its six potential O-glycosylation sites.

Keywords

Deduce Amino Acid Sequence Envelope Glycoprotein Viral Glycoprotein Amino Terminal Region Sequencing cDNA Clone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • William Lapps
    • 1
  • Brenda G. Hogue
    • 1
  • David A. Brian
    • 1
  1. 1.Department of MicrobiologyThe University of TennesseeKnoxvilleUSA

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