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The Function of Drosophila in Genetic Toxicology Testing

  • E. Vogel
  • F. H. Sobels
Part of the Chemical Mutagens book series

Abstract

Chemical compounds in an ever-increasing variety and kind are constantly being introduced into the human environment. Some of these may affect the genetic material. Such effects, when produced in germ cells, lead to an increase of the genetic load of our descendants, while in somatic cells they may result in the development of malignancies. Recent findings suggest a striking overlap between the mutagenic and carcinogenic potential of chemicals that a distinction between the two tends to become an artificial one.

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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • E. Vogel
    • 1
  • F. H. Sobels
    • 1
  1. 1.Department of Radiation Genetics and Chemical Mutagenesis (Sylvius Laboratory)State University of LeidenThe Netherlands

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